A TaqI RFLP in the locus D9S29 on human chromosome 9

A TaqI RFLP identified at the retinoblastoma locus on chromosome 13.

SOURCE/DESCRIPTION: Probe D95HS0.5 is a 0.6 kb fragment subcloned into Blue-scribe a pUCl9 derivative from a bacterio phage library isolated by a cDNA probe of the retinoblastoma gene 1. The fragment is released with the enzymes Hindlll and Sail. POLYMORPHISMS: TaqI identifies a 2 allele polymorphism with a band at 2.1 kb and 1.8 kb with a frequency of 0.97 and 0.03 respectively. There are no c...

A TaqI RFLP for the human arylsulfatase A gene.

TaqI RFLP at D21S137.

Chromosomal Localization: The 3 polymorphic bands were mapped to chromosome 22 using a somatic cell hybrid panel. The 2.1 kb constant band mapped to chromosome lq whereas all other constant bands mapped to chromosome 20. Whereas the active gene for hTOPl is located on chromosome 20ql 1.2—13.1, two pseudogenes are on chromosomes Iq23—24 and 22qll.2-13.1 (2). The sequences of hTOPl and the two ps...

A high-frequency RFLP at the human TFE3 locus on the X chromosome.

A polymorphism of D13S86 from the region 13q14.1 to 13q22 N.P.McHaffie-, R.Houwen,' + , W.Cavenee and D.W.Cox. 2 * 1 Research Institute, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario M5G 1X8, department of Medical Genetics, University of Toronto, Toronto and Ludwig Institute for Cancer Research, Montreal, Canada A high-frequency RFLP at the human TFE3 locus on the X ch...

StuI RFLP in the human ABL locus.

Source/Description: A 3.6 kb EcoRI fragment (lambda ABL3) containing portions of exons 7 and 8 and the intervening intron of the ABL oncogene was isolated from a chromosome 9-specific library (ATCC # LA09NS01) using a 1.7 kb Abelson murine leukemia virus probe (v-abl, ONCOR, Inc.). A single copy 1.8 kb BglII fragment (ABL3) was derived from the original lambda clone and detects the StuI RFLP. P...